The Leishman-Donovan Body and Tropical Splenomegaly

The Leishman-Donovan Body

Leishman-Donovan Infection in Europeans

Sir.?Major Childe's paper in the December issue of the Gazette might induce the belief that the Leishman-Donovan disease rarely affects Europeans. No doubt, other cases have occurred in Bombay as well as elsewhere amongst that class prior to the recognition of the condition as a distinct pathological entity. For instance it is often mistaken for a typical or prolonged enteric fever (paratyphoid...

Leishman-Donovan bodies in the bone marrow biopsy.

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Splenectomy for Tropical Splenomegaly

Splenectomy in tropical splenomegaly.

"Big Spleen Disease"-Hamilton et al. MEBRITCLSH 825 44%. His only treatment has been a 15-day course of primaquine followed by 100 mg. of proguanil daily. This is further evidence for a malarial cause of this syndrome and also for implicating the spleen in the plasma volume changes. The role of the spleen is also shown by a case of Felty's syndrome (Pengelly, 1966), in which a marked reduction ...